2′-Hydroxyflavanone: A Bioactive Compound That Protects against Cancers

Cancer is defined as a multifactorial disease because it exhibits the continuous proliferation of malignant cells. It one principal causes death worldwide, with breast cancer occurrence being highest among women and lung men. Hydroxyflavanones come under category flavonones are further classified 2′-hydroxyflavanone, 4′-hydroxyflavanone, 6-hydroxyflavanone, 7-hydroxyflavanone, etc. Flavonoids constitute approximately 60% total dietary polyphenols. Dietary components such vegetables, fruits, cereals, soybeans, tea chief sources flavonoids, while citrus fruits contain high amount hydroxyflavanones. 2′-Hydroxyflavanone known to have anti-inflammatory, antimutagenic, anticancer activities. Hence, investigated treatment for various diseases, especially cancer. can act chemotherapeutic agent in restricts signal transducer activator transcription 3 pathway (STAT3) some forms